Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | EARP and GARP complex-interacting protein 1 |
Synonyms: | EIPR-1, TSSC1 |
Immunogen: | Recombinant protein corresponding to Mouse EIPR1 |
Uniprot ID: | Q8K0G5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Golgi apparatus |
Product Usage Information
IHC/IF | Human | 1: 800-1: 1600 | liver cancer, lung cancer |
Background
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity).
Images
Immunohistochemistry analysis of paraffin embedded human liver cancer using EIPR1 (GB114481) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded human lung cancer using EIPR1 (GB114481) at dilution of 1: 800 | |
Immunofluorescence analysis of paraffin embedded human liver cancer using EIPR1 (GB114481) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |