Your shopping cart is empty!
Anti-EMAP II/AIMP1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | EMAP II/AIMP1 rabbit polyclonal |
Gene Name: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 |
Synonyms: | Multisynthase complex auxiliary component p43, EMAP-2, Endothelial monocyte-activating polypeptide II, EMAP-II, Emap2, Scye1, Aimp1, p43, SCYE1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse EMAP II/AIMP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 34 kDa |
Observed MW. | 40 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | HeLa, 293T, Jurkat, H1299, A549, HepG2, HT-29, MCF7 |
Background
SCYE1(small inducible cytokine subfamily E, member 1) is also named as EMAP2, AIMP1. The human cDNA encodes a 312-amino acid polypeptide that the predicted 34-kDa precursor can be cleaved to produce an active 20-kDa product. SCYE1 is secreted as a result of various stimuli, including TNF-α, heat shock, and hypoxia, and that it acts as a multifunctional cytokine on both endothelial and immune cells. Defects in AIMP1 are the cause of leukodystrophy hypomyelinating type 3 (HLD3). It has 2 isoforms produced by alternative splicing and the protein can exsit as a dimer.
Images
 | Western blot analysis of AIMP1 (GB113080) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
