Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ERK2 rabbit polyclonal |
Gene Name: | Mitogen-activated protein kinase 1 |
Synonyms: | MAPK1, ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK, mitogen-activated protein kinase 1 |
Immunogen: | Recombinant protein corresponding to Mouse ERK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 100-1: 200 | colon, spleen, lung |
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known asextracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylatesnuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Images
Immunohistochemistry analysis of paraffin-embedded human tonsil using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded human lung using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded human lymphoma using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using ERK2 (GB11370-1) at dilution of 1: 100. |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using ERK2 (GB11370-1) at dilution of 1: 100. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |