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Anti-Endothelin B Receptor/ET-B Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Endothelin B Receptor/ET-B rabbit polyclonal |
Gene Name: | Endothelin receptor type B |
Synonyms: | ABCDS, EDNRB, Endothelin B receptor, ETB, ETBR, ETRB, ET-BR, ET-B, HSCR, HSCR2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Endothelin B Receptor/ET-B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 50 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 15000 | colon, lung |
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Images
 | Western blot analysis of EDNRB (GB113234) at dilution of 1: 15000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
