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| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Epithelial cell adhesion molecule |
Synonyms: | EPCAM, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, epithelial cell adhesion molecule |
Immunogen: | Recombinant protein corresponding to Mouse EpCAM |
Uniprot ID: | |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 35 kDa / 35-40 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | MCF-7, HT29, A-431 |
IHC/IF | Human | 1: 2000-1: 4000 | colon cancer |
Background
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Images
Western blot analysis of EpCAM (GB12274) at dilution of 1: 1000 | |
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using EpCAM (GB12274) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human colon using EpCAM (GB12274) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
