Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Fibrillarin rabbit polyclonal |
Gene Name: | rRNA 2'-O-methyltransferase fibrillarin |
Synonyms: | FBL, FIB, FIB1, fibrillarin, FLRN, RNU3IP1, Histone-glutamine methyltransferase, Nucleolar protein 1, U6 snRNA 2'-O-methyltransferase fibrillarin |
Immunogen: | Recombinant protein corresponding to Mouse Fibrillarin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 34 kDa |
Observed MW. | 34 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | testis, brain, colon |
Background
Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
Images
Western blot analysis of FBL (GB113638) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |