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Anti-Flightless I Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Protein flightless-1 homolog |
Synonyms: | FLI, Fli1, Flightless I, FLII, FLIL, Protein flightless 1 homolog |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Flightless I |
Uniprot ID: | Q9JJ28 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm, Cytoskeleton |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 2000 | colon cancer, breast cancer, lung, heart, skeletal muscle |
Background
May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling (By similarity). Essential for early embryonic development. May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.
Images
| Immunohistochemistry analysis of paraffin embedded human colon cancer using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse heart using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse skeletal muscle using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat heart using Flightless 1 (GB115244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat skeletal muscle using Flightless 1 (GB115244) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
