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Anti-GABA A Receptor alpha 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GABA A Receptor alpha 1 rabbit polyclonal antibody |
Gene Name: | Gamma-aminobutyric acid type A receptor subunit alpha1 |
Synonyms: | ECA4, EJM, GABA A receptor alpha 1, GABAA receptor alpha 1, GABRA1 |
Immunogen: | Recombinant protein corresponding to Mouse GABA A Receptor alpha 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane, Secreted |
Predicted MW. | 52 kDa |
Observed MW. | 52 kDa |
Uniprot ID: | P62812 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1500 | cerebellum, hippocampus, brain |
IHC/IF | Human, Mouse, Rat | 1: 300-1: 600 | cerebellum, brain |
Background
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
Images
 | Western blot analysis of GABRA1 (GB113973) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded mouse brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 300 (200x lens) |
 | Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB113973) at dilution of 1: 400 (200x lens) |
 | Immunohistochemistry of paraffin embedded mouse cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens) |
 | Immunohistochemistry of paraffin embedded rat cerebellum using GABRA1 (GB113973) at dilution of 1: 300 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
