Reactivity: | H & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | G kinase-anchoring protein 1 |
Synonyms: | FKSG21, G kinase anchoring protein 1, GKAP1, GKAP42 |
Immunogen: | Recombinant protein corresponding to Mouse GKAP1 |
Uniprot ID: | Q9JMB0 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Golgi apparatus |
Predicted MW. / Observed MW. | 42 kDa / 45 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 1500 | U-251 MG |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | testis |
Background
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
Images
Western blot analysis of GKAP1 (GB114464) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse testis using GKAP1 (GB114464) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat testis using GKAP1 (GB114464) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded mouse testis using GKAP1 (GB114464) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded rat testis using GKAP1 (GB114464) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |