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| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Glucagon-like peptide 1 |
Synonyms: | GCG, GLP1, GLP2, GRPP, glucagon, Glucagon, GLP-1, GLP, GLP-2, GRPP Oxyntomodulin, OXM, Proglucagon, OXY |
Immunogen: | KLH conjugated Synthetic peptidecorresponding to Mouse GLP1 |
Uniprot ID: | P55095 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 20 kDa / 20 kDa |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 800 | hypothalamus, rectum, brain |
Background
Glucagon is a 29-amino acid peptide hormone secreted from the pancreatic alpha cells with a powerful stimulatory effect on hepatic glucose production acting to increase plasma glucose levels. Glucagon is best known as the counter-regulatory hormone to insulin, and normal glucose homeostasis depends largely on the balanced secretion of insulin and glucagon from the pancreatic beta and alpha cells, respectively.The regulation of glucose metabolism by glucagon is mediated by its direct action on the peripheral tissues such as the liver and also by the brain.
Images
 | Western blot analysis of GLP1 (GB113493) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
