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Anti-GLTPD2 Rabbit pAb (100 μl)
| Reactivity: | M & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Glycolipid transfer protein domain-containing protein 2 |
Synonyms: | GLTPD2 |
Immunogen: | Recombinant protein corresponding to Mouse GLTPD2 |
Uniprot ID: | Q8K0R6 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 34 kDa / 32 kDa |
Product Usage Information
WB | Mouse | 1: 1000-1: 2000 | kidney |
IHC/IF | Mouse | 1: 500-1: 1000 | liver |
Background
The GLTP (glycolipid transfer protein) superfamily is defined by a unique lipid transfer/binding fold (GLTP fold) that accelerate glycolipid intermembrane transfer. GLTPD2 is a 291 amino acid protein that belongs to the GLTP family. The gene encoding GLTPD2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth are both linked to mutations on chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
Images
| Western blot analysis of GLTPD2 (GB114222) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse liver using GLTPD2 (GB114222) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
