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| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GPR3 rabbit polyclonal |
Gene Name: | G-protein coupled receptor 3 |
Synonyms: | ACCA, ACCA orphan receptor, GPR3, GPCR21 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GPR3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 1000 | substantia nigra, brain |
Background
This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse substantia nigra using GPR3 (GB113729) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using GPR3 (GB113729) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
