Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GPRC6A rabbit polyclonal |
Gene Name: | G-protein coupled receptor family C group 6 member A |
Synonyms: | Gprc6a, seven transmembrane helix receptor, Predicted with SOSUI analysis, hGPCR33, GPCR33, GPCR, GPCR 6A, G protein coupled receptor 33, bA86F4.3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GPRC6A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 104 kDa |
Observed MW. | 120 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 3000-1: 6000 | Kidney, liver, lung |
Background
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca2+ and Mg2+. Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.
Images
Western blot analysis of GPRC6A (GB113008) at dilution of 1: 6000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |