Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | GSDMC rabbit polyclonal antibody |
Gene Name: | Gasdermin-C |
Synonyms: | Gasdermin-C1, Melanoma-derived leucine zipper-containing extranuclear factor, mMLZE, Gsdmc, Gasdermin-C |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse GSDMC |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 70 kDa |
Uniprot ID: | Q9BYG8, Q99NB5, P85967 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skin, kidney |
Background
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown.
Images
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Western blot analysis of GSDMC (GB111623) at dilution of 1: 50 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |