Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | PTB domain-containing engulfment adapter protein 1 |
Synonyms: | CED-6, CED6, Cell death protein 6 homolog, GULP, GULP1, Protein GULP |
Immunogen: | Recombinant protein corresponding to Mouse GULP1 |
Uniprot ID: | Q8K2A1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | tonsil, brain |
Background
Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization of various LRP1 ligands, such as PSAP (By similarity). May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Increases cellular levels of GTP-bound ARF6.
Images
Immunohistochemistry analysis of paraffin embedded human tonsil using GULP1 (GB114473) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded mouse Brain using GULP1 (GB114473) at dilution of 1: 800 | |
Immunohistochemistry analysis of paraffin embedded rat Brain using GULP1 (GB114473) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |