Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Gem-associated protein 8 |
Synonyms: | FAM51A1, Gem associated protein 8, Gemin 8, GEMIN8, Protein FAM51A1 |
Immunogen: | Recombinant protein corresponding to Mouse Gemin 8 |
Uniprot ID: | Q8BHE1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 28 kDa / 28-34 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1200 | colon |
Background
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).
Images
Western blot analysis of GEMIN8 (GB114516) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |