Reactivity: | M |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HDAC2 rabbit polyclonal |
Gene Name: | Histone deacetylase 2 |
Synonyms: | HDAC2, HD2, RPD3, YAF1, histone deacetylase 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HDAC2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 3000 | lung cancer, kidney, skeletal, heart, colon |
IF | Human, Mouse, Rat | 1: 500-1: 2000 | lung cancer, kidney, skeletal, heart, colon |
Background
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Images
Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded human kidney using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded mouse skeletal using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded mouse colon using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded mouse kidney using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded mouse heart using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded rat ovary using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded rat heart using HDAC2 (GB11371) at dilution of 1:2000. |
|
Immunohistochemistry analysis of paraffin-embedded rat stomach using HDAC2 (GB11371) at dilution of 1:2000. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |