Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Homeobox expressed in ES cells 1 |
Synonyms: | ANF, hAnf, HESX homeobox 1, HESX1, Homeobox protein ANF, RPX |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HESX1 |
Uniprot ID: | Q61658 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 22 kDa / 21 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1500 | testis, lymph node |
Background
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.
Images
Western blot analysis of HESX1 (GB114746) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |