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Anti-HLA E Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HLA E rabbit polyclonal antibody |
Gene Name: | HLA class I histocompatibility antigen, alpha chain E |
Synonyms: | MHC class I antigen E, sHLA-E, HLA-6.2, HLAE, HLA-E, QA1, Major histocompatibility complex class I E, Lymphocyte antigen |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human HLA E |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 43 kDa |
Uniprot ID: | P13747 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 350-1: 700 | HUVEC |
Background
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Images
 | Western blot analysis of HLAE (GB112510) at dilution of 1: 350 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
