Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | 17-beta-hydroxysteroid dehydrogenase type 6 |
Synonyms: | HSE, RODH, SDR9C6, HSD17B6 |
Immunogen: | Recombinant protein corresponding to Mouse HSD17B6 |
Uniprot ID: | Q9R092 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Microsome membrane Early endosome membrane |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | liver |
Background
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro).
Images
Immunohistochemistry analysis of paraffin embedded human liver using HSD17B6 (GB114159) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse liver using HSD17B6 (GB114159) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded mouse liver using HSD17B6 (GB114159) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |