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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Heat shock 70 kDa protein 1A |
Synonyms: | HSP70-1, HSP70.1, HSPA1, HSP72, Heat Shock 70 KDa Protein 1 |
Immunogen: | Recombinant protein corresponding to Human HSP70 |
Uniprot ID: | P0DMV8 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Predicted MW. / Observed MW. | 70 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, kidney, spleen |
IHC/IF | Human, Mouse, Rat | 1: 700-1: 2000 | myocardial infarction, ovarian cancer |
Background
This protein is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.
Images
| Western blot analysis of HSP70 (GB12244) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human ovarian cancer using HSP70 (GB12244) at dilution of 1: 700 |
| Immunohistochemistry analysis of paraffin embedded mouse myocardial infarction using HSP70 (GB12244) at dilution of 1: 700 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
