Reactivity: | H,M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | IFT81 rabbit polyclonal antibody |
Gene Name: | Intraflagellar transport protein 81 homolog |
Synonyms: | CDV-1, CDV 1R, CDV1, CDV1R, IFT81 |
Immunogen: | Recombinant protein corresponding to Mouse IFT81 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell projection |
Predicted MW. | 79 kDa |
Observed MW. | 85 kDa |
Uniprot ID: | O35594 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 700-1: 1400 | brain, pancreas, kidney |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | lung, ovary |
Background
Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling.; [Isoform CDV-1]: May be involved in cardiac hypertrophy caused by carnitine deficiency.; [Isoform CDV-1R]: May play a role in development of the testis and spermatogenesis.
Images
Western blot analysis of IFT81 (GB114109) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse lung using IFT81 (GB114109) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat lung using IFT81 (GB114109) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse ovary using IFT81 (GB114109) at dilution of 1: 2000 | |
Immunofluorescence of paraffin embedded mouse ovary using IFT81 (GB114109) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |