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Anti-INTS10 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Integrator complex subunit 10 |
Synonyms: | C8orf35, INT10, integrator complex subunit 10, INTS10 |
Immunogen: | Recombinant protein corresponding to Mouse INTS10 |
Uniprot ID: | Q8K2A7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 82 kDa / 70 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 2000- 1: 4000 | testis |
IHC/IF | Mouse | 1: 1000-1: 2000 | hippocampus, striatum |
Background
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.
Images
| Western blot analysis of INTS10 (GB114194) at dilution of 1: 2000 |
| mmunohistochemistry analysis of paraffin embedded mouse hippocampus using INTS10 (GB114194) at dilution of 1: 2000 |
| mmunofluorescence analysis of paraffin embedded mouse striatum using INTS10 (GB114194) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
