Your shopping cart is empty!
Anti-ITGA7 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Integrin alpha-7 |
Synonyms: | alpha7, FLJ25220, Integrin α7, Integrin alpha-7 70 kDa form, Integrin alpha-7 heavy chain, Integrin alpha-7 light chain |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ITGA7 |
Uniprot ID: | Q61738 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 129 kDa / 135 kDa |
Product Usage Information
WB | Human | 1: 300-1: 500 | Jurkat |
Background
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Mice carrying a ITGA7 null allele are viable and fertile, but show progressive muscular dystrophy starting soon after birth, but with a distinct variability in different muscle types. Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Images
| Western blot analysis of ITGA7 (GB115047) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
