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Anti-Junctional Adhesion Molecule 1/JAM-A Rabbit pAb (100 μl)
| Reactivity: | M,R & R & R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | JAM-A rabbit polyclonal |
Gene Name: | Junctional adhesion molecule A |
Synonyms: | JAM-A, Junctional adhesion molecule 1, JAM-1, CD321, F11r, am1, Jcam, Jcam1 |
Immunogen: | Recombinant protein corresponding to Mouse JAM-A |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 33 kDa |
Observed MW. | 35 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 800 | stomach, lung, colon |
IHC | Rat | 1: 500-1: 1500 | spleen, kidney, stomach |
IF | Rat | 1: 500-1: 1500 | lung |
Background
The JAM-A seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Images
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Western blot analysis of JAM-A (GB111265) at dilution of 1: 800 |
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Immunohistochemistry analysis of paraffin-embedded Rat spleen using JAM-A (GB111265) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded Rat kidney using JAM-A (GB111265) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded Rat stomach using JAM-A (GB111265) at dilution of 1: 1500 |
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Immunofluorescent analysis of paraformaldehyde-fixed Rat lung using JAM-A (GB111265) at dilution of 1: 1500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |