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Anti-KAT13C / NCOA2 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KAT13C / NCOA2 rabbit polyclonal antibody |
Gene Name: | Nuclear receptor coactivator 2 |
Synonyms: | GRIP1, MED1, TIF2, Transcriptional intermediary factor 2, Steroid receptor coactivator 2, Ncoa2, NCoA-2, bHLHe75, Class E basic helix-loop-helix protein 75 |
Immunogen: | Recombinant protein corresponding to Mouse KAT13C / NCOA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 158 kDa |
Observed MW. | 160 kDa |
Uniprot ID: | Q61026 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 1000-1: 2000 | cerebral cortex, brain |
Background
Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC1 expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3.
Images
| Western blot analysis of NCOA2 (GB114099) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
