Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KATNB1 rabbit polyclonal antibody |
Gene Name: | Katanin p80 WD40 repeat-containing subunit B1 |
Synonyms: | KAT, Katanin p80 subunit B1, KATNB1, p80 katanin |
Immunogen: | Recombinant protein corresponding to Mouse KATNB1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 73 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | Q8BG40 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 300-1: 1000 | skeletal muscle |
Background
Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome.
Images
Western blot analysis of KATNB1 (GB114101) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |