Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | KDM5A rabbit polyclonal antibody |
Gene Name: | Lysine-specific demethylase 5A |
Synonyms: | Histone demethylase JARID1A, Jumonji/ARID domain-containing protein 1A, Kdm5a, Rbp2, RBBP-2, Jarid1a, Retinoblastoma-binding protein 2 |
Immunogen: | Recombinant protein corresponding to Mouse KDM5A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 192 kDa |
Observed MW. | 192 kDa |
Uniprot ID: | P29375, Q3UXZ9 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | uterus, liver |
Background
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Images
Western blot analysis of kdm5a (GB111087) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |