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Anti-KDM6B / JMJD3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KDM6B / JMJD3 rabbit polyclonal antibody |
Gene Name: | Lysine-specific demethylase 6B |
Synonyms: | Histone demethylase JMJD3, JmjC domain containing protein 3, Jumonji D3, Jumonji domain containing 3, Kdm6b, KIAA0346, Lysine demethylase 6B, Lysine K specific demethylase 6B, Lysine specific demethylase 6B |
Immunogen: | Recombinant protein corresponding to Mouse KDM6B / JMJD3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 176 kDa |
Observed MW. | 176 kDa |
Uniprot ID: | Q5NCY0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 300-1: 600 | brain |
Background
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Images
 | Western blot analysis of KDM6B (GB114024) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
