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Anti-KMT6/EZH2 Mouse mAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Histone-lysine N-methyltransferase EZH2 |
Synonyms: | EZH2, ENX-1, ENX1, EZH1, EZH2b, KMT6, KMT6A, WVS, WVS2, enhancer of zeste 2 polycomb repressive complex 2 subunit |
Immunogen: | Recombinant protein corresponding to Human EZH2 |
Uniprot ID: | Q15910 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 85 kDa / 85-102 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1500 | tonsil, testis |
Background
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Images
| Western blot analysis of EZH2 (GB12272) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using EZH2 (GB12272) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat testis using EZH2 (GB12272) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using EZH2 (GB12272) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
