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Anti-KPNA4 Rabbit pAb (100 μl)
| Reactivity: | H & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | KPNA4 rabbit polyclonal |
Gene Name: | Importin subunit alpha-3 |
Synonyms: | Importin alpha Q1, Qip1, Karyopherin subunit alpha-4, Kpna4, Qip1, SRP3, IPOA3, Importin alpha 4 subunit, Importin alpha 3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse KPNA4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 58 kDa |
Observed MW. | 58 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 800-1: 1600 | testis |
IHC | Mouse, Rat | 1: 3000-1: 6000 | heart |
Background
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Images
| Western blot analysis of KPNA4 (GB113062) at dilution of 1: 1600 |
| Western blot analysis of KPNA4 (GB113062) at dilution of 1: 1600 |
| Immunohistochemistry analysis of paraffin-embedded mouse heart using KPNA4 (GB113062) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using KPNA4 (GB113062) at dilution of 1: 6000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
