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Anti-Kindlin-1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Fermitin family homolog 1 |
Synonyms: | C20orf42, DTGCU2, Fermitin family homolog 1, FERMT1, KIND1, Kindlerin, Kindlin 1, Kindlin syndrome protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Kindlin-1 |
Uniprot ID: | P59113 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 77 kDa / 75 kDa |
Product Usage Information
WB | Human | 1: 2000-1: 3000 | HCT 116, HT-29, 293 |
Background
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites.
Images
| Western blot analysis of FERMT1 (GB114813) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
