Reactivity: | H & M |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | LIM and SH3 domain protein 1 |
Synonyms: | Lasp-1, LASP1, LIM and SH3 protein 1, MLN 50, MLN50, Metastatic lymph node gene 50 protein |
Immunogen: | Recombinant protein corresponding to Mouse LASP1 |
Uniprot ID: | Q61792 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 30 kDa / 38 kDa |
Product Usage Information
WB | Human | 1: 1000-1: 2000 | U-87MG, T47D, A549 |
ICC/IF | Mouse | 1: 50-1: 200 | NIH-3T3 |
Background
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
Images
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |