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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Microtubule-associated proteins 1A/1B light chain 3C |
Synonyms: | LC3C, MAP1A/MAP1B LC3 C, MAP1A/MAP1B light chain 3 C, MAP1LC3C |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human LC3C |
Uniprot ID: | Q9BXW4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton, Membrane |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | lung cancer, placenta |
Background
Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 . Recruits all ATG8 family members to infecting bacteria such as S.typhimurium . May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins .
Images
| Immunohistochemistry analysis of paraffin embedded human placenta using MAP1LC3C (GB114734) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human lung cancer using MAP1LC3C (GB114734) at dilution of 1: 500 |
| Immunofluorescence of paraffin embedded human placenta using MAP1LC3C (GB114734) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
