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Anti-LETM1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | LETM1 rabbit polyclonal |
Gene Name: | Mitochondrial proton/calcium exchanger protein |
Synonyms: | Leucine zipper-EF-hand-containing transmembrane protein 1, Letm1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LETM1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 83 kDa |
Observed MW. | 83 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | heart, liver |
Background
LETM1 is a mitochondrial inner membrane protein. It functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. It served as an anchor protein for complex formation between mitochondria and ribosome, and regulated mitochondrial biogenesis. It was also identified inWolf-Hirschhorn syndrome, and was deleted in nearly all patients with the syndrome. A recent study determined that adenovirus-mediated LETM1 may provide a useful target for designing lung tumor prevention and treatment.
Images
 | Western blot analysis of LETM1 (GB113711) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
