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Anti-LIMD1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | LIM domain-containing protein 1 |
Synonyms: | LIM domains containing 1, LIMD1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LIMD1 |
Uniprot ID: | Q9QXD8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 71 kDa / 71 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 800 | spleen, skeletal muscle |
IHC/IF | Human, Mouse, Rat | 1: 600-1: 1200 | breast cancer, endometrial cancer, renal carcinoma, brain |
Background
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A.
Images
| Western blot analysis of LIMD1 (GB114592) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded human endometrial cancer using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded human renal carcinoma using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded mouse brain using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded rat brain using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunofluorescence analysis of paraffin embedded human breast cancer using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunofluorescence analysis of paraffin embedded mouse brain using LIMD1 (GB114592) at dilution of 1: 600 |
| Immunofluorescence analysis of paraffin embedded rat brain using LIMD1 (GB114592) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
