Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Leucine-rich repeat-containing protein 19 |
Synonyms: | FLJ21302 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse LRRC19 |
Uniprot ID: | Q8BZT5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | colon, spleen |
Background
Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of proinflammatory cytokines . In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances . In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation.
Images
Immunohistochemistry analysis of paraffin embedded rat colon using LRRC19 (GB115104) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded mouse colon using LRRC19 (GB115104) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded human colon using LRRC19 (GB115104) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded rat spleen using LRRC19 (GB115104) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin embedded mouse spleen using LRRC19 (GB115104) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |