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Anti-Leptin Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Leptin rabbit polyclonal |
Gene Name: | Leptin |
Synonyms: | LEPD, leptin, LEP, leptin, OB, Obese protein, Obesity factor, OBS |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Leptin |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1:100-1:200 | colon, stomach, liver, spleen, lung, brain |
IF | Human, Mouse, Rat | 1:100-1:200 | colon, stomach, liver, spleen, lung, brain |
Background
The protein is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism.
Images
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Immunohistochemistry analysis of paraffin-embedded human colon using Leptin (GB11309) at dilution of 1:100 |
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Immunohistochemistry analysis of paraffin-embedded human stomach using Leptin (GB11309) at dilution of 1:100 |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using Leptin (GB11309) at dilution of 1:100 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
