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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Colorectal mutant cancer protein |
Synonyms: | MCC, MCC1, mutated in colorectal cancers, Protein MCC |
Immunogen: | Recombinant protein corresponding to Human MCC |
Uniprot ID: | P23508 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 93 kDa / 98 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, liver |
Background
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
| Western blot analysis of MCC (GB114372) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
