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Anti-MCTS1/MCT-1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Malignant T-cell-amplified sequence 1 |
Synonyms: | MCT-1, MCT1, MCTS1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MCTS1/MCT-1 |
Uniprot ID: | Q9DB27 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1000 | breast cancer, T-cell lymphoma |
Background
Anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constitutively expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
Images
| Immunohistochemistry analysis of paraffin embedded human breast cancer using MCTS1 (GB114599) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human T-cell lymphoma using MCTS1 (GB114599) at dilution of 1: 500 |
| Immunofluorescence analysis of paraffin embedded human T-cell lymphoma using MCTS1 (GB114599) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
