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Anti-MED22 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Mediator of RNA polymerase II transcription subunit 22 |
Synonyms: | MED24, Surf 5, Surf-5, Surfeit 5, Surfeit locus protein 5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MED22 |
Uniprot ID: | Q62276 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 800-1: 2400 | esophageal carcinoma, spleen, brain, liver, smooth muscle |
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Images
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using MED22 (GB114987) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat spleen using MED22 (GB114987) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat brain using MED22 (GB114987) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse liver using MED22 (GB114987) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human smooth muscle using MED22 (GB114987) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
