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Anti-MIST-1 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Class A basic helix-loop-helix protein 15 |
Synonyms: | BHLHA15, BHLHB8, MIST-1, MIST1 |
Immunogen: | Recombinant protein corresponding to Mouse BHLHA15 |
Uniprot ID: | Q9QYC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 22 kDa / 22 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 800-1: 1200 | pancreas |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | pancreas |
Background
Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated . Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3.
Images
| Western blot analysis of BHLHA15 (GB114483) at dilution of 1: 1000 |
| mmunohistochemistry analysis of paraffin embedded mouse pancreas using BHLHA15 (GB114483) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat pancreas using BHLHA15 (GB114483) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded mouse pancreas using BHLHA15 (GB114483) at dilution of 1: 1000 |
| Immunofluorescence analysis of paraffin embedded rat pancreas using BHLHA15 (GB114483) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
