Reactivity: | M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | MAGUK p55 subfamily member 2 |
Synonyms: | Membrane Protein Palmitoylated 2, PALS4, Homolog of DLG A tumor supressor, DLGH2, DLG2, Discs Large Homolog 2, D11BWG0652E, MPP2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MPP2/DLG2 |
Uniprot ID: | Q9WV34 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell projection, Cytoplasm, Cytoskeleton, Membrane, Synapse |
Product Usage Information
IHC/IF | Mouse | 1: 700-1: 2000 | brain |
Background
Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density. In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression. Seems to negatively regulate SRC function in epithelial cells.
Images
Immunohistochemistry analysis of paraffin embedded rat brain using MPP2 (GB114850) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded mouse brain using MPP2 (GB114850) at dilution of 1: 1000 | |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |