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Anti-MRPL58 Rabbit pAb (100 μl)
| Reactivity: | M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Peptidyl-tRNA hydrolase ICT1, mitochondrial |
Synonyms: | DS-1, ICT1 |
Immunogen: | Recombinant protein corresponding to Mouse MRPL58 |
Uniprot ID: | Q8R035 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Predicted MW. / Observed MW. | 23 kDa / 18 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | colon, kidney |
IHC/IF | Human | 1: 500-1: 1000 | colon cancer, esophageal carcinoma |
Background
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit . Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity).
Images
| Western blot analysis of MRPL58 (GB114424) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon cancer using MRPL58 (GB114424) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded human esophageal carcinoma using MRPL58 (GB114424) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
