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Anti-MT4-MMP Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MT4-MMP rabbit polyclonal |
Gene Name: | Matrix metalloproteinase-17 |
Synonyms: | MMP-17, Matrix metalloproteinase 17, MMP17, MT-MMP 4, MT4-MMP, MT4MMP, MTMMP, Membrane type matrix metalloproteinase 4 |
Immunogen: | Recombinant protein corresponding to Mouse MT4-MMP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 64 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain |
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Images
 | Western blot analysis of MT4-MMP (GB113511) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
