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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MTA1 rabbit polyclonal antibody |
Gene Name: | Metastasis-associated protein MTA1 |
Synonyms: | MTA1, Metastasis-associated 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MTA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 81 kDa |
Observed MW. | 81 kDa |
Uniprot ID: | Q13330 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | MCF7, 293T, NIH/3T3 |
Background
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Plays an important role in tumorigenesis, tumor invasion . Plays a role in the regulation of the circadian clock . May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER. With TFCP2L1, promotes establishment and maintenance of pluripotency in embryonic stem cells (ESCs) and inhibits endoderm differentiation (By similarity).
Images
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Western blot analysis of MTA1 (GB111042) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |