Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MTA1 rabbit polyclonal antibody |
Gene Name: | Metastasis-associated protein MTA1 |
Synonyms: | MTA1, Metastasis-associated 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MTA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 81 kDa |
Observed MW. | 81 kDa |
Uniprot ID: | Q13330 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | MCF7, 293T, NIH/3T3 |
Background
Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Plays an important role in tumorigenesis, tumor invasion . Plays a role in the regulation of the circadian clock . May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER. With TFCP2L1, promotes establishment and maintenance of pluripotency in embryonic stem cells (ESCs) and inhibits endoderm differentiation (By similarity).
Images
Western blot analysis of MTA1 (GB111042) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |