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| Reactivity: | H,M,R & H,M |
| Applications: | IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Diphosphomevalonate decarboxylasedecarboxylase) |
Synonyms: | FP17780, MDDase, MPD |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MVD |
Uniprot ID: | Q99JF5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 500-1: 2000 | breast cancer, brain cancer, tonsil, stomach |
ICC/IF | Human, Mouse | 1: 100-1: 600 | HeLa, NIH-3T3 |
Background
Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.
Images
| Immunohistochemistry analysis of paraffin embedded human breast cancer using MVD (GB115083) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded rat brain cancer using MVD (GB115083) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded mouse brain cancer using MVD (GB115083) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded human tonsil using MVD (GB115083) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded rat stomach using MVD (GB115083) at dilution of 1: 600 |
| Immunohistochemistry analysis of paraffin embedded mouse stomach using MVD (GB115083) at dilution of 1: 600 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using MVD (GB115083) at dilution of 1: 400 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using MVD (GB115083) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
