Your shopping cart is empty!
Anti-MYBPC3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | MYBPC3 rabbit polyclonal |
Gene Name: | Myosin-binding protein C, cardiac-type |
Synonyms: | Cardiac MyBP C, CMH4, FHC, MYBP C, MYBPC3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse MYBPC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1000-1: 2000 | heart |
Background
MYBPC3 belongs to the immunoglobulin superfamily and MyBP family. MYBPC3 located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Defects in MYBPC3 are the cause of cardiomyopathy familial hypertrophic type 4 (CMH4). The antibody detects the full length form and the degradation bands around 28-54 kDa in SDS-PAGE.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse heart using MYBPC3 (GB113736) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat heart using MYBPC3 (GB113736) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
