Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | MYOM2 rabbit polyclonal |
Gene Name: | Myomesin 2 |
Synonyms: | Myom2, M band protein, TTNAP, Myomesin family member 2, 165 kDa connectin associated protein, M-protein, Titin associated protein |
Immunogen: | Recombinant protein corresponding to Mouse MYOM2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 165 kDa |
Observed MW. | 165 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart, liver, skeletal muscle |
Background
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical.
Images
Western blot analysis of MYOM2 (GB113170) at dilution of 1: 2000 | |
Western blot analysis of MYOM2 (GB113170) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |